What is PRF?
Platelet-Rich Fibrin (PRF) is a natural treatment derived from your own blood that enhances skin health and healing by leveraging the body's regenerative processes. It is a second-generation version of Platelet-Rich Plasma (PRP) and is considered more advanced due to its enhanced composition and healing potential.
PRF is prepared by drawing a small amount of your blood, spinning it at a lower speed, and collecting a concentrated layer of platelets, white blood cells, and fibrin. Unlike PRP, PRF forms a fibrin matrix, which slowly releases growth factors and promotes collagen production, tissue repair, and skin rejuvenation over time.
Benefits of PRF
- Stimulates collagen production for long-term skin improvement.
- Enhances skin texture, elasticity, and tone.
- Improves under-eye hollows, acne scars, fine lines, and more.
- Works as a 100% natural alternative for rejuvenation treatments.
If you’re looking for a natural and long-lasting solution for skin rejuvenation, PRF is a superior option when compared to PRP, offering enhanced results without the use of chemicals or additives.
PRF vs. PRP: Key Differences
| Benefits | PRF | PRP |
| Growth Factor Release | PRF releases 8–10 times more growth factors, leading to more powerful and long-lasting effects. | PRP releases fewer growth factors, with shorter-lasting benefits. |
| Additives | PRF is 100% natural, with no additives or anticoagulants used during preparation. | PRP requires anticoagulants to prevent blood clotting, making it less natural. |
| Fibrin Matrix | PRF contains a fibrin scaffold, which helps to sustain the release of growth factors over time. | PRP lacks a fibrin matrix, so its effects are more immediate but shorter-lasting. |
| Centrifugation Speed | PRF is spun at a lower speed, preserving platelets and white blood cells. | PRP is spun at a higher speed, which can damage or lose some beneficial components. |
| Longevity | PRF results are gradual and improve over weeks to months, with longer-lasting effects. | PRP provides faster but shorter-lived results as compared to PRF. |
| Applications | PRF is ideal for natural rejuvenation, stimulating collagen, and improving texture and elasticity. | PRP is commonly used for acne scar repairs and skin resurfacing. |
How Does PRF Treatment Work?
1. Blood Draw: A small amount of blood is drawn from your arm, similar to a routine blood test.
2. Centrifugation: The blood is spun at a low speed in a centrifuge, separating the platelets, white blood cells, and fibrin into one concentrated layer.
3. Injection: The PRF is carefully injected into targeted areas, such as under the eyes, cheeks, or scalp, to stimulate collagen production, improve skin texture, and promote natural healing.
4. Fibrin Matrix: The fibrin matrix within PRF acts as a scaffold, gradually releasing growth factors for long-lasting rejuvenation.
PRP/PRF with other Aesthetic Treatments:
PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) are natural, regenerative treatments that can enhance and complement other skin rejuvenation therapies like microneedling, laser therapy, and Morpheus8. Microneedling creates micro-injuries to stimulate collagen, and combining it with PRP or PRF (commonly called the "Vampire Facial") amplifies results by infusing the skin with concentrated growth factors, promoting faster healing, and delivering improved texture and elasticity. At BeautyFix Medspa, we can combine PRF/PRP with Laser Genesis, Microneedling, Morpheus8, or CO2 lasers post-treatment to accelerate healing, reduce inflammation, and enhance collagen remodeling for better skin rejuvenation. Similarly, with Morpheus8, a treatment that combines microneedling with radiofrequency energy to tighten skin and remodel tissue, PRF boosts the production of new collagen and elastin, optimizing outcomes while reducing downtime. Together, these combinations provide comprehensive rejuvenation, addressing multiple skin concerns like fine lines, scars, pigmentation, and elasticity, with both immediate and long-term benefits.
PRF vs Dermal Fillers
At BeautyFix Medspa, we offer a range of advanced treatments to address under-eye concerns, including PRP/PRF and dermal fillers. Both options are highly effective but work in distinct ways to achieve rejuvenation, depending on your goals and preferences. Here’s how these treatments compare and how we can help you decide which one is best for you.
Platelet-Rich Fibrin (PRF)is a natural, regenerative treatment derived from your own blood. By harnessing the body’s natural growth factors, this new treatment stimulates collagen production, improves skin texture, and enhances elasticity over time. This approach is ideal for patients who prefer a natural solution to reduce fine lines, improve under-eye hollows, and rejuvenate their skin. While results from PRF are more subtle and take about three months to fully develop, they are long-lasting and continue to improve as collagen builds with each session. PRF is perfect for those seeking gradual, natural-looking results without the use of preservatives.
In contrast, dermal fillers are a synthetic solution designed to instantly restore lost volume and smooth under-eye hollows or dark circles. With just one treatment, fillers deliver immediate and noticeable improvements, making them an excellent choice for patients who want fast, dramatic results. Depending on the type of filler used, results can last anywhere from several months to a few years, though maintenance treatments are necessary to sustain the effects over time. Dermal fillers are especially effective for addressing volume loss, hollowness, or prominent under-eye shadows, offering a quick fix for a more refreshed and youthful appearance.
Real People. Real Results.
Who is the Ideal Candidate for PRP/PRF Treatments?
PRF (Platelet-Rich Fibrin) is an ideal treatment for individuals seeking a natural approach to skin rejuvenation without synthetic fillers or additives. It is especially effective for those looking to address fine lines, under-eye hollows, aging skin, and reduced elasticity with a natural boost of collagen production. PRF treatments use the body’s own growth factors to stimulate skin regeneration, improve texture, and restore a youthful glow. These treatments are particularly appealing for patients who prioritize subtle, long-term improvements over immediate, synthetic solutions, offering a safe and natural way to achieve smoother, firmer, and more radiant skin.
What to Expect During a PRP/PRF Treatment
1. Preparation:
○ Drink plenty of water and avoid alcohol, aspirin, or NSAIDs a few days prior to treatment.
○ Follow your provider's guidelines regarding medications and skincare.
2. Procedure:
○ Blood Draw: Takes only a few minutes.
○ Centrifuge Processing: PRF requires slower spinning, which takes a few minutes longer than PRP.
○ Injection: PRF or PRP is injected into the treatment areas using a fine needle. Localized numbing may be provided for comfort.
3. Treatment Time:
○ Sessions typically last between 45–60 minutes, depending on the areas being treated.
When Will You See Results from PRF Treatments?
Results develop gradually, with noticeable improvements in 4–12 weeks and long-lasting effects for up to a year or more.
Treatment Areas for PRP/PRF
● Face: Fine lines, wrinkles, under-eye hollows, acne scars, and overall rejuvenation.
● Scalp: Hair restoration for thinning or early-stage hair loss.
● Neck & Décolletage:Skin tightening and rejuvenation.
● Hands: Improves texture and elasticity.
● Breast: Improves volume and creates a subtle lift.
How to Prepare for PRF Treatments?
● Stay hydrated in the days leading up to your treatment.
● Avoid alcohol, caffeine, and smoking for at least 24 hours before treatment.
● Discontinue aspirin and blood-thinning medications under your doctor's guidance.
● Arrive with clean skin and no makeup on the treatment day.
What to Expect Post-Treatment?
● Mild swelling, redness, or bruising, which resolves in a few days.
● Avoid makeup and sun exposure for the first 24–48 hours.
● Results will develop gradually, with follow-up sessions often recommended for optimal results.
How would I choose if PRF is the right treatment for me?
If you’re looking for a natural, long-term approach to enhance your skin’s health and texture, PRF might be the ideal choice for you. However, if you’re looking for a quick and dramatic correction to under-eye hollows or dark circles, dermal fillers could be the better option.
Whether you’re drawn to the natural collagen-boosting effects of PRF or the instant volume provided by dermal fillers, our team of expert injectors will guide you every step of the way. With personalized care and cutting-edge treatments, BeautyFix Medspa is your destination for achieving bright, youthful under-eyes and a refreshed appearance.